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184. White House Rules for Open Access w/ Heather Joseph

The COVID-19 pandemic changed nearly every aspect of our lives. Schools and businesses shut down. Hospitals filled up. And many of us spent months alone or in familial ‘pods.’

But this dark period of global history had some bright spots, and many of them appeared in the scientific community. Rapid at-home testing became ubiquitous. mRNA vaccines were used to immunize millions against the worst outcomes. And funding flowed to scientists in virology, immunology, drug development, air quality and more.

As a society, we learned something else, though: science can save lives. More science, better science, and faster science can save more lives.

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person recycling

108: My Green Lab with Allison Paradise

It’s Monday morning and you arrive in lab a little late. No worries, you drop your tissue culture media into the warming bath, turn on the hood, and head down the hall while things ‘warm up.’

Next stop is the -80 freezer. You dig through the drifting piles of frost and snow, around the boxes of samples with labels that wore off ages ago, and find your quarry. You throw your weight into the door, and manage to get it latched – just barely – and head to the lab.

Once there, you dump yesterday’s gel buffer down the drain and start measuring out agarose and ethidium bromide for today’s experiments. With the gel poured, it’s finally time for coffee. Then maybe you’ll get around to splitting your cells.

It may be an easy morning for a cell biologist, but it was pretty rough on the planet. This week we explore some simple tweaks this busy scientist could make to be greener and more sustainable!

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students celebrating good grades

094: Do Grades Matter in Grad School?

We got an email from a first-year student who seems to love everything about grad school… except the tests.  He’s wondering: Do grades matter?

Dear Josh and Daniel,

I am a first year chemical engineering PhD student and am currently working through a class-filled semester. For two of my classes, my midterm grades were much less than desirable for me. Now, I’m not the quickest when it comes to math, so a lower score in classes like transport compared to other students has been the norm, but these scores are even lower than what I usually expect.

Nerves have been a typical part of my exam state of mind, but past experience has shown I can usually overcome them. I feel like I understand the concepts, and my homework and quiz grades for the class would seem to indicate that. However, the tests have gotten the best of me both times.

I have to maintain a certain GPA and while I don’t know what the final grades will be yet, I feel like I should be doing better.

I guess my real question is, are class grades indicative of whether or not a PhD is right for me?

I have a master’s and have done research for more than 3 years, so I feel that the actual research portion of the program will not be the issue. And every time I get to talk research with my lab group and new advisor, I love it. For now, it just seems like my grades aren’t indicating that I’m a good enough student for the program, and I really don’t want that to be the case. I plan on talking to my advisor about it all soon as well as older grad students.

Thanks for listening and thanks for your show,

Sincerely,

Zachary

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011: The 8.5 Fixes That Will Save Biomedical Science (R)

Josh and Daniel are on the road this week, so we decided to bring you some goodies from the archive.  An 8-ish step plan to save science!  

Biomedical science is broken.  Funding is unpredictable, training programs drag on indefinitely, and some of our best scientists are drawn to careers outside of the university or drowned in paperwork if they stay.  Can anything be done to support research staff and boost lab productivity?

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grad student investing

089: The Grad Student’s Guide to Investing for Retirement

On a graduate student’s stipend, it’s hard to imagine having enough money left over to afford a dinner out, let alone enough to invest for retirement.

But if you can scrape together a few dollars each month, you have a once-in-a-lifetime opportunity to grow that investment. As a grad student, time is on your side.

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